Signal Pathway

Transcription factor

TRE(transcription factor response element)

Amino Acid Deprivation

ATF4/3/2

AACATTGCATCATCCCCGC

Androgen

AR

TGGAGGAACATATTGTATTTATT

Antioxidant Response

NRF2/1

TCACAGTGACTCAGCAAAATT 

ATF6

ATF6

CTCGAGACAGGTGCTGACGTGGCATTC 

C/EBP

C/EBP

ATTGCGCAAT

cAMP/PKA

CREB

TGACGTCA

Cell Cycle

E2F/DP1

TTTCGCGGGAAA

EGR1

EGR1

CGCCCCCGCG 

ER Stress

CBF/NF-Y/YY1

CCTTCACCAATCGGCGGCCTCCACGACG

Heavy Metal Stress

MTF1

GAGCTCTGCACTCCGCCC

Estrogen

Estrogen Receptor (ER)

GTCAGGTCACAGTGACCTGAT

GATA

GATA

GGCATTCTCTATCTGATTGTT

Glucocorticoid

Glucocorticoid Receptor (GR)

GGTACATTTTGTTCT

Heat Shock Response

HSF 

GAACGTTCCCGAA 

HNF4

HNF4

GGCAAAGGTCAT

Hedgehog

GLI

GACCACCCAC

Hypoxia

HIF-1a

TACGTGCT

Interferon Regulatory Factor

IRF1

GGAAGCGAAAATGAAATTGACT

Interferon Type I

STAT1/STAT2

TAGTTTCACTTTCCC

Interferon Gamma

STAT1/STAT1

AGTTTCATATTACTCTAAATC

KLF4

KLF4

 AGGGTGTGGCC

Liver X Receptor

LXR

TGAATGACCAGCAGTAACCTCAGC 

MAPK/ERK

ELK-1/SRF

GGATGTCCATATTAGGA

MAPK/JNK

AP-1

TGAGTCAG

MEF2

MEF2

CTAGCGCTCTAAAAATAACCCT 

Myc

MYC/MAX

CACGTG

Nanog

NANOG

ACCCTTCGCCGATTAAGTACTTAA

NFκB

NFκB

GGGACTTTCC

Notch

RBP-Jκ

CGTGGGAA

Oct4

Oct4

ATGCAAATAA

Pax6

Pax6

GATTTTCACGCTTGAGTTCAC

PI3K/AKT

FOXO

GATCAAGTAAACAACTATGTAAACAA 

PKC/Ca++

NFAT

GGAGGAAAAACTGTTTCATACAGAAGGCGT

PPAR 

PPAR 

TCGACAGGGGACCAGGACAAAGGTCACGTTCGGGAC 

DNA damage

P53

GAACATGTCCCAACATGTTGT

Retinoic Acid

Retinoic Acid Receptor (RAR)

AGGTCACCAGGAGGTCA

Retinoid X

Retinoid X Receptor

AGGTCAC 

Sox2

Sox2

AACAAAGAGT

SP1

SP1

GGGGCGGGGC 

STAT3

STAT3

GTCGACATTTCCCGTAAATCGTCGA

TGFb

SMAD2/SMAD3/SMAD4

AGCCAGACA

Vitamin D

Vitamin D Receptor

gatccacaaGGTTCAcgaGGTTCAcgtccg

Wnt

TCF/LEF

AGATCAAAGGGGGTA

Xenobiotic

AhR

TGAGTTCTCACGCTAGCAGAT